NCT07087587 Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
| NCT ID | NCT07087587 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Cleveland Clinic |
| Condition | Afib |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2025-08-25 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2025-08-25 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe obstructive sleep apnea (OSA).
Eligibility Criteria
Inclusion Criteria: 1. Informed consent 2. Age 18-85 years 3. High burden paroxysmal AF (≥1%) 4. Moderate-severe OSA (AHI ≥ 15) 5. Implanted device with atrial diagnostics 6. Enrolled in remote monitoring Exclusion Criteria: 1. AF ablation \<6 months 2. Valvular abnormalities 3. Excessive daytime sleepiness in safety-critical jobs 4. Plans for ablation during study 5. Non-CPAP OSA treatment 6. Recent device implantation (\<6 months) 7. Central sleep apnea
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07087587 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Afib. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07087587 currently recruiting?
Yes, NCT07087587 is actively recruiting participants. Contact the research team at CHUNGM@ccf.org for enrollment information.
Where is the NCT07087587 trial being conducted?
This trial is being conducted at Cleveland, United States, Seattle, United States.
Who is sponsoring the NCT07087587 clinical trial?
NCT07087587 is sponsored by The Cleveland Clinic. The trial plans to enroll 20 participants.