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Recruiting NCT07792746

NCT07792746 Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure

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Clinical Trial Summary
NCT ID NCT07792746
Status Recruiting
Phase
Sponsor Clinique du Millenaire
Condition Obstructive Sleep Apnea (OSA)
Study Type OBSERVATIONAL
Enrollment 200 participants
Start Date 2026-02-18
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Continuous Positive Airway Pressure

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 200 participants in total. It began in 2026-02-18 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease. Emerging biomarkers, including sleep apnea-specific hypoxic burden, pulse wave amplitude drop index, and heart rate response, may provide additional information on cardiovascular vulnerability. This prospective multicenter observational study will investigate the association between these biomarkers, measured from the diagnostic sleep study, and adherence to continuous positive airway pressure (CPAP) therapy after three months. Symptoms, quality of life, clinical characteristics, and changes in biomarkers under continuous positive airway pressure will also be evaluated.

Eligibility Criteria

Inclusion Criteria: * Newly diagnosed obstructive sleep apnea with an indication for continuous positive airway pressure therapy * Age older than 18 years * Written informed consent obtained Exclusion Criteria: * Continuous positive airway pressure treatment during the preceding 3 months * Medical contraindication to continuous positive airway pressure therapy * Concomitant condition likely to affect adherence to continuous positive airway pressure, including severe cognitive impairment or an unstable psychiatric disorder

Contact & Investigator

Central Contact

Francois FB Bughin, MD, PhD

✉ fbughin@hotmail.com

📞 0033761783081

Frequently Asked Questions

Who can join the NCT07792746 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Obstructive Sleep Apnea (OSA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07792746 currently recruiting?

Yes, NCT07792746 is actively recruiting participants. Contact the research team at fbughin@hotmail.com for enrollment information.

Where is the NCT07792746 trial being conducted?

This trial is being conducted at Montpellier, France.

Who is sponsoring the NCT07792746 clinical trial?

NCT07792746 is sponsored by Clinique du Millenaire. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology