NCT07650955 Single Infrapubic Versus Bilateral Subinguinal Microsurgical Varicocelectomy
| NCT ID | NCT07650955 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Beni-Suef University |
| Condition | Bilateral Varicocele |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-06-08 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2026-06-08 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Bilateral varicocele is commonly treated by microsurgical varicocelectomy. The conventional bilateral subinguinal approach usually requires two separate skin incisions, one on each side. A single midline infrapubic approach may allow bilateral microsurgical repair through one incision and may reduce access-related morbidity. This prospective randomized controlled trial will compare single infrapubic microsurgical bilateral varicocelectomy with conventional bilateral subinguinal microsurgical varicocelectomy in adult men with clinically palpable bilateral varicocele. The study will evaluate postoperative pain, analgesic requirement, time to return to normal daily activity, operative time, scar satisfaction, wound complications, recurrence, and other safety outcomes during follow-up.
Eligibility Criteria
Inclusion Criteria: * Male patients aged 18 to 45 years. * Clinically palpable bilateral varicocele, grade II or grade III. * Diagnosis confirmed by color Doppler ultrasound. * Infertility for at least 12 months and/or abnormal semen analysis. * Female partner evaluation performed or planned to exclude major uncorrected female-factor infertility. * Patient fit for surgery and anesthesia. * Written informed consent provided by the participant. Exclusion Criteria: * Subclinical varicocele detected only by Doppler ultrasound. * Unilateral varicocele. * Recurrent varicocele after previous surgery, embolization, or sclerotherapy. * Previous inguinal, scrotal, pelvic, or penile surgery likely to distort surgical anatomy. * Associated inguinal hernia, hydrocele, spermatocele, epididymal cyst, or other scrotal condition requiring simultaneous surgery. * Azoospermia, especially suspected non-obstructive azoospermia. * Active urinary tract or genital infection. * Coagulopathy or anticoagulant therapy that cannot be safely interrupted. * Severe obesity, defined as body mass index greater than 40 kg/m², or any anatomical condition preventing safe exposure by either surgical approach. * Refusal to participate or inability to complete follow-up.
Contact & Investigator
Hany F Badawy, MD
PRINCIPAL INVESTIGATOR
Faculty of medicine Beni-Suef University
Frequently Asked Questions
Who can join the NCT07650955 clinical trial?
This trial is open to male participants only, aged 18 Years or older, up to 45 Years, studying Bilateral Varicocele. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07650955 currently recruiting?
Yes, NCT07650955 is actively recruiting participants. Contact the research team at HANYFATHY86@GMAIL.COM for enrollment information.
Where is the NCT07650955 trial being conducted?
This trial is being conducted at Banī Suwayf, Egypt.
Who is sponsoring the NCT07650955 clinical trial?
NCT07650955 is sponsored by Beni-Suef University. The principal investigator is Hany F Badawy, MD at Faculty of medicine Beni-Suef University. The trial plans to enroll 40 participants.