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Recruiting NCT06264024

NCT06264024 Simultaneous pHototherapeutic Keratectomy and corneAl Collagen cRosslinking in Eyes With Keratoconus: a Randomized Trial (SHARK)

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Clinical Trial Summary
NCT ID NCT06264024
Status Recruiting
Phase
Sponsor Oslo University Hospital
Condition Keratoconus
Study Type INTERVENTIONAL
Enrollment 81 participants
Start Date 2024-02-12
Primary Completion 2025-05-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Corneal collagen cross linking (CXL)Transepithelial phototherapeutic keratectomy (t-PTK)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 81 participants in total. It began in 2024-02-12 with a primary completion date of 2025-05-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to compare CXL with combined treatment with CXL and t-PTK. The main questions it aims to answer are whether combined treatment can give better visual acuity and if the treatments are equally safe.

Eligibility Criteria

Inclusion Criteria: * Patients must be 18 years or older at the time of signing the informed consent form. There is no upper age limit. * Progressive keratoconus with indication for CXL * Corneal thickness ≥ 420 μm Exclusion Criteria: * Other eye disease causing visual impairment

Contact & Investigator

Central Contact

Olav Kristianslund, MD, PhD

✉ olakri@ous-hf.no

📞 +4722118545

Frequently Asked Questions

Who can join the NCT06264024 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Keratoconus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06264024 currently recruiting?

Yes, NCT06264024 is actively recruiting participants. Contact the research team at olakri@ous-hf.no for enrollment information.

Where is the NCT06264024 trial being conducted?

This trial is being conducted at Oslo, Norway.

Who is sponsoring the NCT06264024 clinical trial?

NCT06264024 is sponsored by Oslo University Hospital. The trial plans to enroll 81 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology