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Recruiting NCT06105411

Siderophore-labelled Positron Emission Tomography for Correlating Invasive Fungal InfeCtions

Trial Parameters

Condition Invasive Fungal Infections
Sponsor Peter MacCallum Cancer Centre, Australia
Study Type OBSERVATIONAL
Phase N/A
Enrollment 10
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-12-01
Completion 2026-10
Interventions
68Ga-labelled TAFC PET/CT scan

Brief Summary

This trial will demonstrate localised uptake of a radiolabelled fungal component (siderophore) in areas of known specific invasive fungal (Aspergillus) infection.

Eligibility Criteria

Inclusion Criteria: 1. Patient has provided written informed consent 2. Aged 18 years or older at written informed consent 3. Within 2 weeks of proven or probable or possible invasive fungal infection (IFI) diagnosis as per EORTC criteria 4. Imaging consistent with invasive pulmonary aspergillosis on CT or FDG-PET/CT with lesions at least 8mm in diameter 5. Patient is willing and able to comply with the protocol for the duration of the study including scheduled visits such as follow up Exclusion Criteria: 1. Women who are pregnant or lactating. 2. Iron infusion within one week prior to scan

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