NCT07902466 Short-Term Effects of Manual Therapy Prior to Neuromotor Therapy in Children With Cerebral Palsy
| NCT ID | NCT07902466 |
| Status | Recruiting |
| Phase | — |
| Sponsor | LIFE - Research and Care Institute - Santa Lucia IRCCS |
| Condition | Cerebral Palsy (CP) |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2026-10-15 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2026-10-15 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This pilot study aims to evaluate the immediate, short-term biomechanical and neuromuscular effects of lower limb manual therapy applied as a preparatory phase prior to functional neuromotor rehabilitation in children with spastic cerebral palsy (hemiplegic and diplegic forms). Using a prospective self-controlled design, 20 children will be assessed under four experimental conditions (baseline, post-manual therapy, post-functional therapy, and post-combined manual + functional therapy) to determine if manual techniques enhance gait parameters and motor execution.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of spastic Cerebral Palsy with lower limb involvement (hemiplegia or diplegia). * Age between 12 months and 10 years. * Gross Motor Function Classification System (GMFCS) level I, II, III, or IV. * Modified Ashworth Scale (MAS) score ≤ 3 in the lower limbs. Exclusion Criteria: * Botulinum toxin injection in the lower limbs within the past 6 months. * Prior functional orthopedic or neurosurgical procedures on the lower limbs. * Concurrent participation in other experimental clinical studies involving the lower limbs. * Cognitive impairment preventing comprehension of required motor tasks.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07902466 clinical trial?
This trial is open to participants of all sexes, aged 12 Months or older, up to 10 Years, studying Cerebral Palsy (CP). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07902466 currently recruiting?
Yes, NCT07902466 is actively recruiting participants. Contact the research team at c.fantini@hsantalucia.it for enrollment information.
Where is the NCT07902466 trial being conducted?
This trial is being conducted at Roma, Italy.
Who is sponsoring the NCT07902466 clinical trial?
NCT07902466 is sponsored by LIFE - Research and Care Institute - Santa Lucia IRCCS. The trial plans to enroll 20 participants.
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