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Recruiting Phase 4 NCT03821857

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

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Trial Parameters

Condition Alzheimer Disease
Sponsor Mayo Clinic
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 614
Sex FEMALE
Min Age 60 Years
Max Age N/A
Start Date 2019-06-27
Completion 2030-05
Interventions
18-F-Flortaucipir

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Brief Summary

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

Eligibility Criteria

Mayo Clinic Rochester- Inclusion Criteria: * Women who previously participated in this study * Currently aged 60 years and older * More than six months post chemotherapy or major surgery requiring general anesthesia * Willing and able to sign informed consent Exclusion Criteria: * Not able to read and speak English * In hospice * Claustrophobic * If undergoing Tau imaging, cannot have QT Prolongation Mayo Clinic Jacksonville- Inclusion Criteria: * African American Women * Currently aged 60 years and older * More than six months post chemotherapy or major surgery requiring general anesthesia * Willing and able to sign informed consent Exclusion Criteria: * Not able to read and speak English * In hospice * Claustrophobic * If undergoing Tau imaging, cannot have QT Prolongation

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