NCT07468929 Serum Inflammatory Protein Concentration During Dental Treatment
| NCT ID | NCT07468929 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ohio State University |
| Condition | Periodontal Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-07-13 |
| Primary Completion | 2027-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2026-07-13 with a primary completion date of 2027-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to study the molecular markers of stress in blood samples from people who are having periodontal surgery. The main question it aims to answer are: * How do the levels of inflammatory molecules in the blood change during a periodontal surgery? * How are the levels of inflammatory molecules in a person having surgery different from the levels in a person having a nonsurgical procedure? * Participants will be people who are having a periodontal surgery or a nonsurgical periodontal treatment as part of their dental care. Participants will be asked to let the investigator take blood samples from them before, during, and after the procedure is being done. The blood will later be analyzed for substances in the blood that are associated with inflammation.
Eligibility Criteria
Inclusion Criteria: * Adults 21-75 years of age * Systemically healthy * Non-smoker * scheduled to receive nonsurgical or surgical periodontal treatment under IV sedation Exclusion Criteria: * Patients who have localized form of the disease (less than 30% of available tooth/implant sites are affected with the disease) * Non-english speaking individuals since informed consent form will be in English only. * Patients with uncontrolled systemic diseases (such as metabolic diseases, obesity, diabetes, high blood pressure) since these types of chronic inflammatory challenges would cause increase levels of circulatory serum pro-inflammatory markers. * Pregnant patients (pregnancy will be reported by the patient) since pregnancy itself would affect circulatory serum pro-inflammatory markers. * Patients who are not willing to have blood drawing for the study purpose. * Patients who are not willing to sign research related consent form.
Contact & Investigator
Binnaz Leblebibioglu, DDS, MS, PhD
PRINCIPAL INVESTIGATOR
Ohio State University
Frequently Asked Questions
Who can join the NCT07468929 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 75 Years, studying Periodontal Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07468929 currently recruiting?
Yes, NCT07468929 is actively recruiting participants. Visit ClinicalTrials.gov or contact Ohio State University to inquire about joining.
Where is the NCT07468929 trial being conducted?
This trial is being conducted at Columbus, United States.
Who is sponsoring the NCT07468929 clinical trial?
NCT07468929 is sponsored by Ohio State University. The principal investigator is Binnaz Leblebibioglu, DDS, MS, PhD at Ohio State University. The trial plans to enroll 30 participants.