NCT07824518 Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction
| NCT ID | NCT07824518 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universidad Complutense de Madrid |
| Condition | Periodontal Defects After Third Molar Extraction |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-09-01 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-09-01 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study investigates the healing of periodontal defects on the distal surface of the second lower molars after the surgical extraction of impacted third molars. Specifically, it compares the effectiveness of autologous tooth graft particles (derived from the extracted third molar) with bovine xenograft particles, using blood clot healing as a control.
Eligibility Criteria
Inclusion Criteria: * Adults (≥18 years old) of any sex, able to understand and follow study instructions. * Patients requiring bilateral surgical extraction of impacted lower third molars in horizontal or mesioangular position. * Presence of both lower second molars. * Classified as ASA I or ASA II (according to the American Society of Anesthesiologists). * Willingness to participate voluntarily and sign informed consent. Exclusion Criteria: * Age under 18 years. * ASA physical status III, IV, V, or VI. * Pregnant or breastfeeding women. * Immunosuppressed patients. * Current treatment with NSAIDs, anticoagulants, or acetylsalicylic acid. * Previous or current treatment with bisphosphonates. * Presence of oral dysplasia or precancerous lesions.
Contact & Investigator
José María Martínez-González, MD,DMD,PhD,MDV
STUDY DIRECTOR
Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid
Frequently Asked Questions
Who can join the NCT07824518 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Periodontal Defects After Third Molar Extraction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07824518 currently recruiting?
Yes, NCT07824518 is actively recruiting participants. Contact the research team at migrui02@ucm.es for enrollment information.
Where is the NCT07824518 trial being conducted?
This trial is being conducted at Madrid, Spain.
Who is sponsoring the NCT07824518 clinical trial?
NCT07824518 is sponsored by Universidad Complutense de Madrid. The principal investigator is José María Martínez-González, MD,DMD,PhD,MDV at Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid. The trial plans to enroll 30 participants.