| NCT ID | NCT05235867 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, Los Angeles |
| Condition | Anorexia in Adolescence |
| Study Type | OBSERVATIONAL |
| Enrollment | 10 participants |
| Start Date | 2022-02-01 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 10 participants in total. It began in 2022-02-01 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with restrictive-type anorexia nervosa who are admitted to the hospital for feeding often urinate excessive amounts. Others have changes in the way that they handle acid and base. These issues prolong hospitalizations. Current data suggest that one hormone--named secretin--may control both urine output and how the body handles acid and base. This study will evaluate whether secretin levels are different in anorexic patients who urinate an excessive amount compared to those who urinate normal amounts. For this study, patients will have one extra blood draw before and after one meal during their hospitalization. The blood draw before the meal coincides with a standard of care blood draw. Also after the meal, subjects will be asked to provide one extra urine sample. Information from subject's medical records will also be used.
Eligibility Criteria
Inclusion Criteria: * Group 1: * male and female patients * age 13-24 years * diagnosis of restrictive-type anorexia nervosa * hospitalization for nutritional support * \>4 cc/kg/day of urine output (a.k.a. "fluid dumpers"; n=5) * Group 2: * male and female patients * age 13-24 years * diagnosis of restrictive-type anorexia nervosa * hospitalization for nutritional support * \<2 cc/kg/d of urine output (a.k.a. "non-dumpers"; n=5) Exclusion Criteria: * 5150 hold * Anti-depressant, anti-psychotic, or anticonvulsant medications * Previous hospitalization within the past 6 months * Underlying metabolic disorder not related to anorexia nervosa (including chronic kidney disease, renal tubular disorders, and underlying endocrine disorders) * Pregnancy * NG or G-tube feeds after day 2 of hospitalization * \> 10% of nutritional needs from supplemental feeds
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05235867 clinical trial?
This trial is open to participants of all sexes, aged 13 Years or older, up to 24 Years, studying Anorexia in Adolescence. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05235867 currently recruiting?
Yes, NCT05235867 is actively recruiting participants. Contact the research team at mbmacaraig@mednet.ucla.edu for enrollment information.
Where is the NCT05235867 trial being conducted?
This trial is being conducted at Los Angeles, United States.
Who is sponsoring the NCT05235867 clinical trial?
NCT05235867 is sponsored by University of California, Los Angeles. The trial plans to enroll 10 participants.