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Recruiting NCT04022109

Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach

Trial Parameters

Condition Gastric Cancer
Sponsor University of Latvia
Study Type OBSERVATIONAL
Phase N/A
Enrollment 5,000
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2019-11-01
Completion 2022-12
Interventions
Breath sampling for VOC detectionSurgery material collection for VOC headspace analysisUpper endoscopy

Brief Summary

The study is aimed to determine the potential of volatile marker testing for gastric cancer screening. The study will be addressing the role of confounding factors, including lifestyle factors, diet, smoking as well as addressing the potential role of microbiota in the composition of exhaled volatile markers.

Eligibility Criteria

Inclusion Criteria: * Patients with verified gastric cancer (Group 1 \& 2) * Patients undergoing or having undergone upper endoscopy according to clinical indications (Group 3 \& 5) * Average-risk population group aged 40-64 at inclusion without alarm symptoms (Group 4) * Motivation to participate in the study * Physical status allowing volatile marker sampling and other procedures within the protocol * Signed consent Exclusion Criteria: * Known other active cancer * Ventilation problems, airway obstruction * Unwillingness or inability to co-operate

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