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Recruiting Phase 1 NCT06137755

NCT06137755 Safety and Immunogenicity of CVI-VZV-001 for Prevention of Herpes Zoster in Healthy Adults Age 50 Years and Above

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Clinical Trial Summary
NCT ID NCT06137755
Status Recruiting
Phase Phase 1
Sponsor CHA Vaccine Institute Co., Ltd.
Condition Vaccine-Preventable Diseases
Study Type INTERVENTIONAL
Enrollment 32 participants
Start Date 2023-03-15
Primary Completion 2025-03-21

Trial Parameters

Condition Vaccine-Preventable Diseases
Sponsor CHA Vaccine Institute Co., Ltd.
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 32
Sex ALL
Min Age 50 Years
Max Age 64 Years
Start Date 2023-03-15
Completion 2025-03-21
Interventions
CVI-VZV-001Shingrix

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Brief Summary

The purpose of this study is to evaluate the safety and immunogenicity of the investigational medicinal product, CVI-VZV-001.

Eligibility Criteria

Inclusion Criteria: 1. Healthy adults over 50 years old and under 65 years old 2. Those who voluntarily decided to participate and gave written consent after hearing and understanding the detailed explanation of this clinical trial 3. Women with childbearing potential and those who agree to use the contraceptive method\* permitted up to 3 months after the final vaccination for clinical trials (\* Combination use such as hormonal contraception, intrathyroidal device (IUD (Intrauterine device) or IUS (Intrauterine system), vasectomy, tubal stomy, double block method (cervical cap, use with contraceptive diaphragm) 4. Women of childbearing potential with negative result at pregnancy test before vaccination for clinical trials. Exclusion Criteria: 1. Those with a past history of shingles before screening 2. Persons with hypersensitivity to clinical investigational products or the ingredients of clinical investigational products 3. Those with thrombocytopenia or other coagulation disorders

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