NCT06199401 Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery
| NCT ID | NCT06199401 |
| Status | Recruiting |
| Phase | — |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University |
| Condition | Type A Aortic Dissection |
| Study Type | INTERVENTIONAL |
| Enrollment | 680 participants |
| Start Date | 2024-01-11 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 680 participants in total. It began in 2024-01-11 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a national, multicenter, open-label, randomized, controlled, endpoint-blinded clinical trial of patients diagnosed with ATAAD and undergoing "Sun's procedure" coordinated by the First Affiliated Hospital of Xi'an Jiaotong University, China. Per the protocol, "Sun's procedure" combined with "XJ-Procedure" in the anastomosis of the aortic root and Sun's procedure combined with regular suturing methods of the aortic root will be compared.
Eligibility Criteria
Inclusion Criteria: * Age 18-70 years; * Patients with ATAAD attending the relevant department who have been assessed by a clinician as needing "Sun's procedure". Exclusion Criteria: * Severe aortic root involvement (root diameter \>45 mm, root tear, severe destruction of the aortic root, combined valve disease); * Combined coronary artery disease requiring concomitant coronary revascularization; * Prior aortic or cardiac surgery; * Preoperative severe malperfusion syndromes such as: severe cerebral complications (acute cerebral infarction, cerebral hemorrhage, coma, etc.); malperfusion of abdominal organs or lower extremities \>12 h; * Preoperative combination of severe single or multiple organ failure; * Pregnant women; * Refused to sign the informed consent form and refused to participate in this study.
Contact & Investigator
Yang Yan
PRINCIPAL INVESTIGATOR
First Affiliated Hospital Xi'an Jiaotong University
Frequently Asked Questions
Who can join the NCT06199401 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Type A Aortic Dissection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06199401 currently recruiting?
Yes, NCT06199401 is actively recruiting participants. Contact the research team at yangyan3@xjtu.edu.cn for enrollment information.
Where is the NCT06199401 trial being conducted?
This trial is being conducted at Xi'an, China.
Who is sponsoring the NCT06199401 clinical trial?
NCT06199401 is sponsored by First Affiliated Hospital Xi'an Jiaotong University. The principal investigator is Yang Yan at First Affiliated Hospital Xi'an Jiaotong University. The trial plans to enroll 680 participants.