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Recruiting Phase 3 NCT06223269

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

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Trial Parameters

Condition Burns Degree Third
Sponsor XenoTherapeutics, Inc.
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 50
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-05-09
Completion 2025-12
Interventions
Skin XenotransplantAutograft(ing)

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Brief Summary

To evaluate the safety and efficacy of realSKIN® to provide complete wound closure of mixed-depth, full-thickness burn wounds as an alternative treatment to autografting.

Eligibility Criteria

Inclusion Criteria: 1. The subject, or the subject's legally authorized representative (LAR), provides written informed consent to participate in this study 2. Males or females age greater than or equal to 18 years old 3. Total Burn Surface Area (TBSA) \<50% to include mixed depth and full-thickness burn wounds as defined as "primarily full-thickness (FT) and deep-partial (DPT) thermal burns (e.g. \>60% of the total burn area should be FT and DPT) before debridement", and full-thickness burns for which surgical intervention is clinically indicated 4. Having a mixed depth thermal burn wound including full thickness requiring skin grafting 5. Biological females must have a negative serum pregnancy test at Screening and must not be nursing 6. All subjects must agree to use a protocol-approved method of contraception for a minimum of 3 months following realSKIN placement, which includes a barrier method plus one or more of the following: * Hormonal contraceptives (e.g., birth control pills

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