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Recruiting Phase 4 NCT06848946

NCT06848946 Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone

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Clinical Trial Summary
NCT ID NCT06848946
Status Recruiting
Phase Phase 4
Sponsor Glaukos Corporation
Condition Glaucoma, Open-angle
Study Type INTERVENTIONAL
Enrollment 132 participants
Start Date 2025-01-13
Primary Completion 2026-08

Eligibility & Interventions

Sex All sexes
Min Age 45 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
iDose TR (travoprost intracameral implant) 75 µg in conjunction with cataract surgerySham procedure in conjunction with cataract surgery

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 132 participants in total. It began in 2025-01-13 with a primary completion date of 2026-08.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This trial will evaluate the safety and IOP -lowering efficacy of administering an iDose TR (travoprost intracameral implant) in conjunction with cataract surgery compared to cataract surgery alone

Eligibility Criteria

Inclusion Criteria: * Cataract diagnosis: clinically significant age-related cataract eligible for phacoemulsification in the study eye. * OAG or OHT diagnosis: either OAG (i.e. primary, pseudoexfoliation, or pigmentary glaucoma) or OHT in the study eye (i.e., eye to undergo cataract surgery) Exclusion Criteria: * Active corneal inflammation or edema. * Retinal disorders not associated with glaucoma.

Contact & Investigator

Central Contact

Study Manager

✉ ClinicalResearch@glaukos.com

📞 949-739-8749

Principal Investigator

Study Director

STUDY CHAIR

Glaukos Corporation

Frequently Asked Questions

Who can join the NCT06848946 clinical trial?

This trial is open to participants of all sexes, aged 45 Years or older, studying Glaucoma, Open-angle. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06848946 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT06848946 currently recruiting?

Yes, NCT06848946 is actively recruiting participants. Contact the research team at ClinicalResearch@glaukos.com for enrollment information.

Where is the NCT06848946 trial being conducted?

This trial is being conducted at Kenosha, United States.

Who is sponsoring the NCT06848946 clinical trial?

NCT06848946 is sponsored by Glaukos Corporation. The principal investigator is Study Director at Glaukos Corporation. The trial plans to enroll 132 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology