NCT06802952 RTMS for CHR Based on Personalized Targets Using Magnetoencephalography
| NCT ID | NCT06802952 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Mental Health Center |
| Condition | Clinical High-risk Syndrome of Psychosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 26 participants |
| Start Date | 2025-02-07 |
| Primary Completion | 2026-12-31 |
Trial Parameters
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Brief Summary
This study is an before-after study in the same subject, which enrolled 26 individuals with high-risk psychiatric syndrome (CHR). The target of subjects intervention relies on the results of magnetoencephalography localization. The medication and dosage remain unchanged during the intervention period or not yet taking antipsychotic medication. The investigators assume that the intervention targets for each CHR subject are individualized.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of Clinical High-Risk Syndrome for Psychosis * Must be able to right-handed * Primary school education or above * Understand and sign a written informed consent form (jointly signed by the guardian and the participant if under 18 years old) Exclusion Criteria: * Major physical illnesses (organic lesions such as sensory and motor disorders, neurological disorders, and traumatic brain injury) * Taboo symptoms for rTMS treatment (such as intracranial metal implants) * Metal (including orthodontic treatment, dental implants) and tattoos inside the body * Claustrophobia