NCT06427317 Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment
| NCT ID | NCT06427317 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Imperial College London |
| Condition | Infections, Bacterial |
| Study Type | OBSERVATIONAL |
| Enrollment | 323 participants |
| Start Date | 2024-03-19 |
| Primary Completion | 2027-03-19 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 323 participants in total. It began in 2024-03-19 with a primary completion date of 2027-03-19.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary aim of the study is to determine the proportion of individuals receiving beta-lactam antibiotics at Imperial College Healthcare NHS Trust in whom drug concentration targets are achieved.
Eligibility Criteria
Inclusion Criteria: 18 years of age or above. * Under follow-up for management of infection at Imperial College NHS Trust * Received a beta-lactam antibiotic within the last 48 hours (or are planned to start imminently). * Provides informed written consent see below, or lacks capacity to provide consent because of one of the following conditions (and declaration provided by personal consultee): * Delirium which may be caused or exacerbated by having an infection. * Suspected/confirmed central nervous system infection. * Critical illness requiring sedation and/or intubation and ventilation which is caused by or exacerbated by having an infection. Exclusion Criteria: * Less than 18 years of age * Severe anaemia (Hb \< 70g/l) * Platelets \< 50x10\^9/l, INR \>1.5 or other known blood clotting impairment * Patient with terminal diagnosis receiving palliative care input who may experience distress if approached for this study. * Enrolled in a clinical trial which stipulates exclusion from other studies including observational studies. * Patients with restricted liberty, prisoners or under legal protection.
Contact & Investigator
Alison Holmes, MD
PRINCIPAL INVESTIGATOR
Imperial College London
Frequently Asked Questions
Who can join the NCT06427317 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Infections, Bacterial. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06427317 currently recruiting?
Yes, NCT06427317 is actively recruiting participants. Contact the research team at suzanne.williams@imperial.ac.uk for enrollment information.
Where is the NCT06427317 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT06427317 clinical trial?
NCT06427317 is sponsored by Imperial College London. The principal investigator is Alison Holmes, MD at Imperial College London. The trial plans to enroll 323 participants.