NCT07003672 Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
| NCT ID | NCT07003672 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan University Hospital |
| Condition | Weaning Failure |
| Study Type | OBSERVATIONAL |
| Enrollment | 120 participants |
| Start Date | 2025-01-16 |
| Primary Completion | 2028-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 120 participants in total. It began in 2025-01-16 with a primary completion date of 2028-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This project focuses on the analysis of the correlation between transpulmonary driving pressure and uneven lung ventilation and regional lung compliance in patients using prolonged mechanical ventilation (PMV), in order to understand the clinical occurrence of failure of the final spontaneous breathing test and inability to breathe. Respiratory physiology impairments in patients successfully discharged from respirators.
Eligibility Criteria
Inclusion Criteria: * Post-tracheostomy patients who are transferred to the subacute respiratory care ward of National Taiwan University Hospital must use respirators for at least 14 days; * Be at least 20 years old; * The oxygen concentration required when using the respirator does not exceed 50% Exclusion Criteria: * The vital signs are unstable or require continuous use of vasopressors; * Pregnancy; * Chronic obstructive pulmonary disease or asthma; * Those who have contraindications to the placement of esophageal pressure balloons, such as abnormal blood coagulation, esophageal varices, and those who have undergone esophageal or gastric surgery in the past six months; * Those who have contraindications to the use of electrical impedance tomography, such as heart rhythm regulators.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07003672 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Weaning Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07003672 currently recruiting?
Yes, NCT07003672 is actively recruiting participants. Contact the research team at jsjerng@ntu.edu.tw for enrollment information.
Where is the NCT07003672 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT07003672 clinical trial?
NCT07003672 is sponsored by National Taiwan University Hospital. The trial plans to enroll 120 participants.