NCT05678413 Role of Paclitaxel in Stricture Urethra
| NCT ID | NCT05678413 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Al-Azhar University |
| Condition | Stricture Urethra |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2022-06-01 |
| Primary Completion | 2025-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2022-06-01 with a primary completion date of 2025-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Stricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates. Multiple trial were performed to improve the outcomes of DVIU. Various intralesional injections were used. in this trial we will evaluate intralesional paclitaxel injection following DVIU.
Eligibility Criteria
Inclusion Criteria: * Anterior urethral stricture * Short strictures (less than 2 cm) * International Prostate Symptom Score less than 11 and maximum flow rate \< 15 ml per second. * No previous treatment for stricture disease Exclusion Criteria: * Recurrent cases * Prior pelvic radiation * Associated other pathology or unresolved confounding etiologies (e.g. bladder neck contracture, neurogenic bladder, benign prostatic hyperplasia) were excluded.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05678413 clinical trial?
This trial is open to male participants only, aged 18 Years or older, studying Stricture Urethra. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05678413 currently recruiting?
Yes, NCT05678413 is actively recruiting participants. Contact the research team at prof_mohamed_fawzy@yahoo.com for enrollment information.
Where is the NCT05678413 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT05678413 clinical trial?
NCT05678413 is sponsored by Al-Azhar University. The trial plans to enroll 200 participants.