NCT05725096 Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population
| NCT ID | NCT05725096 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Zhang longjiang,MD |
| Condition | Statin |
| Study Type | INTERVENTIONAL |
| Enrollment | 3,400 participants |
| Start Date | 2023-06-28 |
| Primary Completion | 2025-03 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor control compared with traditional CHD prevention strategy, guided by a cardiovascular risk score.
Eligibility Criteria
Inclusion Criteria: 1. Nanjing residents who have no plans to leave in the next 5 years 2. Aged from 40 to 69 years 3. Free of any known clinically cardiovascular disease Able to comprehend and sign an informed consent form Exclusion Criteria: 1. Serious liver dysfunction, defined as AST or ALT \> 3 times the normal upper limit 2. Chronic kidney disease (CKD) \> stage 4, defined as eGFR \< 30 ml/min/1.73 m2 3. Prior CCTA or invasive coronary angiography within the last 5 years 4. Any contraindications for CCTA 5. Previous use of statin or non-statin lipid-lowering medication (such as ezetimibe, PCSK9 inhibitor and XueZhiKang) 6. Life expectancy \< 3 years 7. Other reasons the researcher deems inappropriate to attend