NCT07109180 Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA)
| NCT ID | NCT07109180 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
| Condition | Chronic Pancreatitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 28 participants |
| Start Date | 2025-04-16 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 28 participants in total. It began in 2025-04-16 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.
Eligibility Criteria
Inclusion Criteria: * At least 18 years old * Indication for (extended or partial) lateral pancreaticojejunostomy as agreed during multidisciplinary team meeting based on symptomatic chronic pancreatitis (i.e. morphine dependent pain or recurrent acute flares of pancreatitis, at least 3 episodes per year) and a dilated pancreatic duct of ≥ 5 mm, with a non-enlarged pancreatic head \< 40 mm * Confirmed CP, according to the M-ANNHEIM diagnostic Criteria24 * Eligible for both an robot-assisted and open approach * Obtained written informed consent Exclusion Criteria: * Suspected or confirmed current pancreatic cancer * ASA classification ≥ 4 * Other painful conditions aside from CP, with pain difficult to discriminate from CP pain * Prior pancreatic surgery * Pregnancy
Contact & Investigator
M.G. Besselink, Amsterdam UMC
PRINCIPAL INVESTIGATOR
prof. dr.
Frequently Asked Questions
Who can join the NCT07109180 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Chronic Pancreatitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07109180 currently recruiting?
Yes, NCT07109180 is actively recruiting participants. Contact the research team at e.kilinc@amsterdamumc.nl for enrollment information.
Where is the NCT07109180 trial being conducted?
This trial is being conducted at Amsterdam, Netherlands.
Who is sponsoring the NCT07109180 clinical trial?
NCT07109180 is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA). The principal investigator is M.G. Besselink, Amsterdam UMC at prof. dr.. The trial plans to enroll 28 participants.