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Recruiting NCT07258784

NCT07258784 RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis

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Clinical Trial Summary
NCT ID NCT07258784
Status Recruiting
Phase
Sponsor University of Maryland, Baltimore
Condition Tracheal Stenosis
Study Type OBSERVATIONAL
Enrollment 10 participants
Start Date 2025-09-11
Primary Completion 2026-09-10

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 80 Years
Study Type OBSERVATIONAL
Interventions
Biopsy or surgery

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 10 participants in total. It began in 2025-09-11 with a primary completion date of 2026-09-10.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatrogenic etiologies such as intubation or tracheostomy , as well as autoimmune diseases and being idiopathic. Patients typically undergoes endoscopic or surgical interventions to open up the airways. This project will analyze resected or biopsied tissue from patients with benign tracheal stenosis to define disease-specific RNA expression profiles.

Eligibility Criteria

Inclusion Criteria: * Patients with benign tracheal stenosis Exclusion Criteria: * Malignancy. active infection

Contact & Investigator

Central Contact

Chenchen Zhang, MD

✉ chenchen.zhang@som.umaryland.edu

📞 14103288141

Frequently Asked Questions

Who can join the NCT07258784 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Tracheal Stenosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07258784 currently recruiting?

Yes, NCT07258784 is actively recruiting participants. Contact the research team at chenchen.zhang@som.umaryland.edu for enrollment information.

Where is the NCT07258784 trial being conducted?

This trial is being conducted at Baltimore, United States.

Who is sponsoring the NCT07258784 clinical trial?

NCT07258784 is sponsored by University of Maryland, Baltimore. The trial plans to enroll 10 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology