NCT07850128 Risk of Cervical Cancer Following Incident, Persistent and History-unknown HPV Detection
| NCT ID | NCT07850128 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Cervical Cancer Screening |
| Study Type | OBSERVATIONAL |
| Enrollment | 130,000 participants |
| Start Date | 2025-10-31 |
| Primary Completion | 2025-11-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 130,000 participants in total. It began in 2025-10-31 with a primary completion date of 2025-11-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this register-based retrospective observational study is to understand the risk of cervical cancer following incident, persistent and history-unknown HPV detection by HPV genotype in healthy women participating in HPV-based cervical screening. The main questions it aims to answer are: 1. Whether an incident HPV detection with certain HPV genotypes has low risk of cervical cancer in 3 to 5 years thus does not need further clinical assessment before the next screening test? 2. How risky a persistent HPV detection is, and whether persistent detection of any high-risk HPV genotype warrant immediate clinical assessment? 3. How risky a HPV detection is, if no previous HPV test result is available? As being a register-based retrospective observational study, study subjects will not be asked to do any specific task for this study.
Eligibility Criteria
Inclusion Criteria: * Women living in the Great Stockholm Region in Sweden, at cervical screening ages (age 22-70 years), and having had an HPV positive result in primary HPV test during 2014-2023 Exclusion Criteria: * Women without valid personal identity number in the population registry
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07850128 clinical trial?
This trial is open to female participants only, aged 22 Years or older, up to 70 Years, studying Cervical Cancer Screening. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07850128 currently recruiting?
Yes, NCT07850128 is actively recruiting participants. Contact the research team at jiangrong.wang@ki.se for enrollment information.
Where is the NCT07850128 trial being conducted?
This trial is being conducted at Stockholm, Sweden.
Who is sponsoring the NCT07850128 clinical trial?
NCT07850128 is sponsored by Karolinska Institutet. The trial plans to enroll 130,000 participants.
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