NCT06868888 Rheological Functions of Erythrocyte in ESRD
| NCT ID | NCT06868888 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chang Gung Memorial Hospital |
| Condition | End-stage Renal Disease (ESRD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2022-08-24 |
| Primary Completion | 2025-03-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2022-08-24 with a primary completion date of 2025-03-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
End-stage renal disease (ESRD) disrupts erythrocyte deformability due to osmotic imbalances, oxidative stress, and uremic toxins, leading to impaired microcirculation and oxygen transport. Dysregulation of ion channels, particularly the Gardos channel, exacerbates dehydration and eryptosis, further compromising vascular integrity. Given the critical role of erythrocyte flexibility in oxygen delivery, this study investigates its relationship with aerobic capacity in ESRD patients, highlighting potential mechanisms of microvascular dysfunction
Eligibility Criteria
Inclusion Criteria: * Receiving hemodialysis and medication at least for 6 weeks * Kt/V score \> 1.2 Exclusion Criteria: * Under 20 years-old * Hyperkalemia occurs within 3 month * Having orthopedic or muscular diseases * Other concerned medical, psychological or physiological diseases * Pregnancy * Other exercise contraindications
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06868888 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying End-stage Renal Disease (ESRD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06868888 currently recruiting?
Yes, NCT06868888 is actively recruiting participants. Contact the research team at s5492@mail.cgu.edu.tw for enrollment information.
Where is the NCT06868888 trial being conducted?
This trial is being conducted at Taoyuan, Taiwan.
Who is sponsoring the NCT06868888 clinical trial?
NCT06868888 is sponsored by Chang Gung Memorial Hospital. The trial plans to enroll 40 participants.