Trial Parameters
Brief Summary
Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.
Eligibility Criteria
Inclusion Criteria: * Histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cell carcinoma (ESCC) undergoing esophagectomy * Pathologic staged T3 tumors (pT3) Exclusion Criteria: * Pathologic staged T0-2 (pT0-2) or T4 tumors (pT4) * Patients with histologic types other than EAC or ESCC, dysplasia or carcinoma in situ without tumor invasion, * Patients undergoing salvage esophagectomy * Evidence of distant metastatic disease * Patients with a positive proximal or distal margin