NCT04451278 RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy
| NCT ID | NCT04451278 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Fondation Ophtalmologique Adolphe de Rothschild |
| Condition | Epilepsy |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2020-10-30 |
| Primary Completion | 2027-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2020-10-30 with a primary completion date of 2027-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Resting-state functional MRI (r-fMRI) has emerged in recent years to analyze resting networks. It allows, without active participation of the patients, to identify and analyze the different functional brain networks. The analysis of r-fMRI can be done thanks to the graph theory, which is based on the based on the calculation of quantifiable parameters applied to the functional network studied, making it possible to assess its effectiveness. To the knowledge of the investigators, no study has used graph theory applied to r-fMRI data in order to obtain parameters useful for the useful parameters for the individual prognosis of children who have to be operation for drug-resistant lesional epilepsy.
Eligibility Criteria
Inclusion Criteria: * Patient aged between 6 and 18 years * Receiving an MRI for lesional drug-resistant epilepsy * Affiliated or beneficiary of a social security plan * Whose parents or guardians have received information about the study and have given their express consent to participate in the study Exclusion Criteria: * Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women) * History of intracranial surgery * MRI performed under general anesthesia
Contact & Investigator
Sidney KRYSTAL
PRINCIPAL INVESTIGATOR
Adolphe de Rothschild Fondation Hospital
Frequently Asked Questions
Who can join the NCT04451278 clinical trial?
This trial is open to participants of all sexes, aged 6 Years or older, up to 18 Years, studying Epilepsy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04451278 currently recruiting?
Yes, NCT04451278 is actively recruiting participants. Contact the research team at skrystal@for.paris for enrollment information.
Where is the NCT04451278 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT04451278 clinical trial?
NCT04451278 is sponsored by Fondation Ophtalmologique Adolphe de Rothschild. The principal investigator is Sidney KRYSTAL at Adolphe de Rothschild Fondation Hospital. The trial plans to enroll 200 participants.
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