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Recruiting NCT05185141

Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness

Trial Parameters

Condition Hemodynamic Instability
Sponsor Johannes Gutenberg University Mainz
Study Type OBSERVATIONAL
Phase N/A
Enrollment 84
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2022-01-11
Completion 2025-03

Brief Summary

The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.

Eligibility Criteria

Inclusion Criteria: * Age 18-80 years * written informed consent * scheduled major abdominal surgery Exclusion Criteria: * Age \<18 or \>80 years * pregnancy * SIRS or sepsis * any kind of cardiac arrhythmia * known valve disease * known heart failure * any kind of known carotid stenosis * carotid doppler peak velocity \>182 cm/s before baseline measurement (expected stenosis) * missing indication for invasive arterial blood pressure monitoring (IBP) not related to the study * peripheral artery disease (PAD) * BMI \> 35 kg/m2 * intraabdominal hypertension * ASA-PSC of 4 * severe lung disease (e.g. COPD grade 3, fibrosis) * esophageal disease of any kind * participation in another clinical study

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