NCT05185141 Respiratory Variation of Carotid Doppler Peak Velocity (CDPV) for Non-invasive Prediction of Fluid Responsiveness
| NCT ID | NCT05185141 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johannes Gutenberg University Mainz |
| Condition | Hemodynamic Instability |
| Study Type | OBSERVATIONAL |
| Enrollment | 84 participants |
| Start Date | 2022-01-11 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 84 participants in total. It began in 2022-01-11 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to assess respiratory variation of carotid doppler peak velocity (∆CDPV) for prediction of fluid responsiveness during major abdominal surgery.
Eligibility Criteria
Inclusion Criteria: * Age 18-80 years * written informed consent * scheduled major abdominal surgery Exclusion Criteria: * Age \<18 or \>80 years * pregnancy * SIRS or sepsis * any kind of cardiac arrhythmia * known valve disease * known heart failure * any kind of known carotid stenosis * carotid doppler peak velocity \>182 cm/s before baseline measurement (expected stenosis) * missing indication for invasive arterial blood pressure monitoring (IBP) not related to the study * peripheral artery disease (PAD) * BMI \> 35 kg/m2 * intraabdominal hypertension * ASA-PSC of 4 * severe lung disease (e.g. COPD grade 3, fibrosis) * esophageal disease of any kind * participation in another clinical study
Contact & Investigator
Gunther J Pestel, M.D., Ph.D.
STUDY CHAIR
Johannes Gutenberg University Medical Center, Dpt. of Anesthesiology
Frequently Asked Questions
Who can join the NCT05185141 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Hemodynamic Instability. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05185141 currently recruiting?
Yes, NCT05185141 is actively recruiting participants. Contact the research team at johannes.wirkus@unimedizin-mainz.de for enrollment information.
Where is the NCT05185141 trial being conducted?
This trial is being conducted at Mainz, Germany.
Who is sponsoring the NCT05185141 clinical trial?
NCT05185141 is sponsored by Johannes Gutenberg University Mainz. The principal investigator is Gunther J Pestel, M.D., Ph.D. at Johannes Gutenberg University Medical Center, Dpt. of Anesthesiology. The trial plans to enroll 84 participants.