NCT07538102 Respiratory Physiotherapy and Diaphragm Thickness in Ventilated ICU Patients
| NCT ID | NCT07538102 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hitit University |
| Condition | Diaphragm Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 66 participants |
| Start Date | 2025-08-01 |
| Primary Completion | 2026-05-01 |
Trial Parameters
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Brief Summary
This study aims to evaluate the effect of respiratory physiotherapy on diaphragm thickness in patients receiving mechanical ventilation support in the intensive care unit. Thinning and dysfunction of the diaphragm muscle observed during mechanical ventilation complicate the extubation process and increase the risk of respiratory failure in patients. Diaphragm dysfunction prolongs ventilator use and increases ICU mortality. The main objective of this research is to determine whether respiratory physiotherapy has protective or ameliorative effects on diaphragm muscle structure and function, to optimize the ventilator weaning process, and to provide scientific contributions to the field of respiratory rehabilitation. Changes in diaphragm thickness will be objectively evaluated using ultrasonography, and the aim is to obtain evidence-based data on the effectiveness of respiratory physiotherapy.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Mechanically ventilated for at least 5 days * Hemodynamically stable * Unconscious (Glasgow Coma Scale indicating impaired consciousness) * Informed consent obtained from legal representatives Exclusion Criteria: * Neuromuscular disease * Traumatic diaphragm injury * Thoracic deformity causing mechanical impairment of respiration * Terminal-stage patients * Patients in whom respiratory physiotherapy is contraindicated * Presence of a cardiac pacemaker or implantable cardioverter-defibrillator (ICD)