NCT05030207 Respiratory Adaptive Computed Tomography: Feasibility Study on Real-Time Gated 4DCT for Lung Cancer Radiotherapy
| NCT ID | NCT05030207 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Sydney |
| Condition | Lung Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-05-15 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2024-05-15 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study does not involve a therapeutic intervention as standard radiation therapy treatment will be prescribed. This study involves one additional 4DCT scan (i.e. the Real-Time Gated 4DCT scan) acquired immediately before or following the conventional 4DCT scan. This will take place on the day of the patient's treatment simulation, as per the current standard of care. The scanning sequence (i.e. conventional first versus gated first) will be randomised. The Real-Time Gated 4DCT is anticipated to take longer than the conventional 4DCT scan, due to its gated (beam-pause) nature. However, upper limits for timing will be implemented in the software, and the scan aborted for highly erratic breathing traces that would not benefit from a Real-Time Gated 4DCT scan.
Eligibility Criteria
Inclusion Criteria: * 18 years or older * Have the ability to give informed consent * A diagnosis of lung cancer with an indication for radiation therapy * Radiation therapy treatment involving the acquisition of a 4DCT scan for treatment planning Exclusion Criteria: * Pregnant women * Patients \<18 years * Patients who in the opinion of the treating physician could not tolerate the extra time on the CT couch for an extra scan
Contact & Investigator
Ricky O'Brien, PhD
PRINCIPAL INVESTIGATOR
University of Sydney
Frequently Asked Questions
Who can join the NCT05030207 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05030207 currently recruiting?
Yes, NCT05030207 is actively recruiting participants. Contact the research team at Shona.Silvester@sydney.edu.au for enrollment information.
Where is the NCT05030207 trial being conducted?
This trial is being conducted at Blacktown, Australia.
Who is sponsoring the NCT05030207 clinical trial?
NCT05030207 is sponsored by University of Sydney. The principal investigator is Ricky O'Brien, PhD at University of Sydney. The trial plans to enroll 30 participants.
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