NCT06917053 Renal Perfusion and the Development of AKI Following Traumatic Injury
| NCT ID | NCT06917053 |
| Status | Recruiting |
| Phase | — |
| Sponsor | King's College Hospital NHS Trust |
| Condition | Traumatic Haemorrhagic Shock |
| Study Type | OBSERVATIONAL |
| Enrollment | 20 participants |
| Start Date | 2024-04-13 |
| Primary Completion | 2026-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 20 participants in total. It began in 2024-04-13 with a primary completion date of 2026-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known to develop hypoperfusion of the renal cortex, little is known regarding intra-renal perfusion changes in THS. The aim of the current study is to investigate the effects of THS on renal microcirculatory perfusion.
Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * Within 24 hours of ICU admission following traumatic injury * Received any blood products during initial resuscitation * Lactate \> 2 mmol/l at any stage prior to study enrolment Exclusion Criteria: * Known intolerance to Sonovue or any other ultrasound contrast agent * Patients with un-survivable injuries / not expected to survive 24 hours in whom the intent of treatment is palliative * Known CKD 4 or end stage renal failure * Pregnancy
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06917053 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Traumatic Haemorrhagic Shock. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06917053 currently recruiting?
Yes, NCT06917053 is actively recruiting participants. Contact the research team at sam.hutchings@nhs.net for enrollment information.
Where is the NCT06917053 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT06917053 clinical trial?
NCT06917053 is sponsored by King's College Hospital NHS Trust. The trial plans to enroll 20 participants.