NCT07711132 Remineralizing Effect of Nano-eggshell, Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), and Sodium Fluoride on Initial Enamel Caries
| NCT ID | NCT07711132 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mansoura University |
| Condition | Initial Dental Caries |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2025-12-20 |
| Primary Completion | 2026-12-20 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2025-12-20 with a primary completion date of 2026-12-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled clinical trial aims to evaluate and compare the remineralizing effect of nano-eggshell varnish, CPP-ACP paste (GC Tooth Mousse), and sodium fluoride varnish on initial enamel caries among adolescents aged 15-20 years. Participants will be randomly allocated into three groups. Remineralization and caries activity will be assessed using DIAGNOdent readings, International Caries Classification and Management System (ICCMS) criteria, and the decayed, missed, and filled surfaces (DMFS) index over a 12-month follow-up period.
Eligibility Criteria
Inclusion Criteria: Patients' ages should be 15-20 years. Patients should have at least three to four teeth with ICDAS II scores of 1-2. Patients should have moderate-to-high caries risk. Exclusion Criteria: Known hypersensitivity to one of the components of the material under study. Systemic disorders or medication interfering with normal salivary flow.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07711132 clinical trial?
This trial is open to participants of all sexes, aged 15 Years or older, up to 20 Years, studying Initial Dental Caries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07711132 currently recruiting?
Yes, NCT07711132 is actively recruiting participants. Contact the research team at ghada.ezzat91@yahoo.com for enrollment information.
Where is the NCT07711132 trial being conducted?
This trial is being conducted at Al Mansurah, Egypt.
Who is sponsoring the NCT07711132 clinical trial?
NCT07711132 is sponsored by Mansoura University. The trial plans to enroll 90 participants.