NCT07483853 Reliability and Validation of the WB-MRI Radiological Score in CRMO
| NCT ID | NCT07483853 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna |
| Condition | Chronic Recurrent Multifocal Osteomyelitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 15 participants |
| Start Date | 2027-01-01 |
| Primary Completion | 2027-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 15 participants in total. It began in 2027-01-01 with a primary completion date of 2027-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study evaluates the inter-observer reliability of a standardized WB-MRI scoring system for CRMO and its consistency with the PedCNO clinical score. It also investigates whether changes in the radiologic score mirror therapeutic response, supporting a more objective clinical-radiological disease assessment.
Eligibility Criteria
Inclusion Criteria: * Patients with a diagnosis of CRMO according to the international Bristol clinical and radiologic criteria, followed at the Pediatric Rheumatology Clinic of the Pediatric Unit, IRCCS AOU Bologna, Sant'Orsola Hospital; * Age under 18 years at the time of CRMO diagnosis; * At least one WB-MRI performed as part of routine clinical follow-up between January 2015 and the start date of the study; * Availability of complete clinical documentation (including reports, radiologic images, and clinical information) sufficient to apply both the WB-MRI score and the PedCNO score; * Obtain informed consent. Exclusion Criteria: \- Alternative diagnoses accounting for the bone lesions (e.g., infections, neoplasms).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07483853 clinical trial?
This trial is open to participants of all sexes, up to 32 Years, studying Chronic Recurrent Multifocal Osteomyelitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07483853 currently recruiting?
Yes, NCT07483853 is actively recruiting participants. Contact the research team at angela.miniaci@aosp.bo.it for enrollment information.
Where is the NCT07483853 trial being conducted?
This trial is being conducted at Bologna, Italy.
Who is sponsoring the NCT07483853 clinical trial?
NCT07483853 is sponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna. The trial plans to enroll 15 participants.