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Recruiting NCT04956549

Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI)

Trial Parameters

Condition Dementia of Alzheimer Type
Sponsor Pennington Biomedical Research Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 144
Sex ALL
Min Age 60 Years
Max Age N/A
Start Date 2021-06-01
Completion 2026-03-31
Interventions
Physical activity programSuccessful Aging

Brief Summary

The RAATE-MCI proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. RAATE-MCI is a 52-week randomized controlled trial. 144 African American adults aged 60 and older will be recruited.

Eligibility Criteria

Inclusion Criteria: 1. are African American (self-identify) 2. are 60 and older 3. are physically capable of exercise 4. are willing to accept randomization 5. are willing to attend group sessions 6. plan to live in the study area over the next 13 months and capable of traveling to designated study facility for clinic visits and intervention sessions for the next year 7. are free of conditions (e.g. uncontrolled asthma, severe sickle cell disease, etc.) that would make regular exercise unsafe as deemed by the medical investigator 8. have not engaged in regular physical activity 9. have a Short Physical Performance Battery ≥4 10. physically capable of exercise 11. are unable to utilize devices and/or applications as required for study participation 12. willing to attend group sessions 13. willing to allow researchers to use data for research purposes after study participation is completed 14. meet criteria for MCI as defined by the NIA-AA research framework a. cognitive performance belo

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