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Recruiting NCT06143137

NCT06143137 Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up

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Clinical Trial Summary
NCT ID NCT06143137
Status Recruiting
Phase
Sponsor Artcline GmbH
Condition Severe Sepsis
Study Type OBSERVATIONAL
Enrollment 142 participants
Start Date 2024-01-01
Primary Completion 2029-12-31

Trial Parameters

Condition Severe Sepsis
Sponsor Artcline GmbH
Study Type OBSERVATIONAL
Phase N/A
Enrollment 142
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2024-01-01
Completion 2029-12-31

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Brief Summary

Subjects previously enrolled / randomized in the ReActIF-ICE (Recovery from acute immune failure in septic shock by immune cell extracorporeal terapy - immune competence enhancement) study received either standard sepsis treatment (control group) or standard sepsis treatment and additionally the ARTICE treatment (treatment group) during their index hospitalization. All subjects are followed up for 90 days after enrollment. In this long term follow up study, the enrolled subjects shall be followed up beyond 90 days for up to 5 years.

Eligibility Criteria

Inclusion Criteria: 1. Subject or legal surrogate is willing and able to provide written informed consent and comply with all protocol requirements or the implementation of other established procedures according to the local regulations of the contributing center to include subjects who are unable to provide informed consent. 2. Subject was enrolled in the ReActIF-ICE study and successfully passed the Day 2 re-evaluation of that trial. Exclusion Criteria: * none

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