Recruiting NCT05356286

Recording of Intraoperative Spinal Cord Stimulation and Monitoring

Trial Parameters

Condition Cervical Stenosis

Sponsor University of California, Los Angeles

Study Type INTERVENTIONAL

Phase N/A

Enrollment 150

Sex ALL

Min Age 18 Years

Max Age N/A

Start Date 2011-01-21

Completion 2027-01-22

All Conditions

Cervical Stenosis Disk, Herniated Spondylosis

Interventions

epidural electrical stimulation

Brief Summary

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Eligibility Criteria

Inclusion Criteria: * Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized. Exclusion Criteria: * none

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