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Recruiting NCT05991895

NCT05991895 Real-World Study of Iruplinalkib in the Treatment of ALK-Positive Non-Small Cell Lung Cancer

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Clinical Trial Summary
NCT ID NCT05991895
Status Recruiting
Phase
Sponsor Jinming Yu
Condition Non-small Cell Lung Cancer (NSCLC)
Study Type OBSERVATIONAL
Enrollment 5,000 participants
Start Date 2023-07-24
Primary Completion 2026-07

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Iruplinalkib

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 5,000 participants in total. It began in 2023-07-24 with a primary completion date of 2026-07.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is a national multicenter real-world investigation aimed at evaluating the real-world effectiveness and safety of Iruplinalkib in the treatment of ALK-positive NSCLC in China. The study aims to enroll ALK-positive NSCLC patients who have undergone treatment with Iruplinalkib prior to enrollment. Demographic information, medical history, Iruplinalkib-containing treatment regimens, clinical outcomes, adverse events, and related data will be collected for all enrolled patients. As this study is a real-world investigation, treatment procedures, visit schedules, and examinations will be based on the routine clinical practice of physicians. The primary sources of data for this study will mainly consist of patients' routine medical records or healthcare documentation.

Eligibility Criteria

Inclusion Criteria: * Patients willingly contribute their clinical data for this study * Patients with ALK-positive non-small cell lung cancer * Age ≥ 18 years * Patients who have undergone treatment with Iruplinalkib. Exclusion Criteria: * Known pregnant or lactating females * Patients with interstitial lung diseases, drug-related pneumonitis, or radiation pneumonitis require ongoing medical intervention.

Contact & Investigator

Central Contact

Jinming Yu, PhD

✉ jn7984729@public.jn.sd.cn

📞 8613806406293

Principal Investigator

JinMing Yu, PhD

PRINCIPAL INVESTIGATOR

Shandong Cancer Hospital and Institute

Frequently Asked Questions

Who can join the NCT05991895 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Non-small Cell Lung Cancer (NSCLC). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05991895 currently recruiting?

Yes, NCT05991895 is actively recruiting participants. Contact the research team at jn7984729@public.jn.sd.cn for enrollment information.

Where is the NCT05991895 trial being conducted?

This trial is being conducted at Jinan, China.

Who is sponsoring the NCT05991895 clinical trial?

NCT05991895 is sponsored by Jinming Yu. The principal investigator is JinMing Yu, PhD at Shandong Cancer Hospital and Institute. The trial plans to enroll 5,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology