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Recruiting NCT06862869

NCT06862869 Real World Clinical Outcomes of Resected ALK-Positive Early Stage NSCLC Patients Treated With Alectinib as Adjuvant Therapy

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Clinical Trial Summary
NCT ID NCT06862869
Status Recruiting
Phase
Sponsor Hoffmann-La Roche
Condition Carcinoma, Non-Small-Cell Lung
Study Type OBSERVATIONAL
Enrollment 800 participants
Start Date 2025-04-30
Primary Completion 2029-10-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Alectinib

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 800 participants in total. It began in 2025-04-30 with a primary completion date of 2029-10-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is a multicenter, prospective, cohort study designed to evaluate the clinical outcomes and characteristics of resected stage II-IIIB anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer (NSCLC) adult patients treated with Alectinib as adjuvant therapy in China.

Eligibility Criteria

Inclusion Criteria: * Histologically-confirmed stage II-IIIA or selected IIIB (T3N2) NSCLC as per the American Joint Committee on Cancer and International Union Against Cancer (UICC/AJCC), 8th edition * ALK positive * Postoperative NSCLC patients who have undergone complete resection * Had taken Alectinib monotherapy without prior systemic therapy (including other ALK-TKIs or chemotherapy) as adjuvant† therapy for resected stage II-IIIB ALKpositive NSCLC and the time from the first dose to enrollment was no more than 28 days Exclusion Criteria: * Patients participating in interventional study of adjuvant treatment * Pregnant, lactating, or breastfeeding women

Contact & Investigator

Central Contact

Reference Study ID Number: ML45766 https://forpatients.roche.com/ No attachments to email below.

✉ global-roche-genentech-trials@gene.com

📞 888-662-6728 (U.S. and Canada)

Principal Investigator

Clinical Trials

STUDY DIRECTOR

Hoffmann-La Roche

Frequently Asked Questions

Who can join the NCT06862869 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Carcinoma, Non-Small-Cell Lung. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06862869 currently recruiting?

Yes, NCT06862869 is actively recruiting participants. Contact the research team at global-roche-genentech-trials@gene.com for enrollment information.

Where is the NCT06862869 trial being conducted?

This trial is being conducted at Zhanjiang, China, Guangzhou, China, Kaifeng, China, Zhengzhou, China and 11 additional locations.

Who is sponsoring the NCT06862869 clinical trial?

NCT06862869 is sponsored by Hoffmann-La Roche. The principal investigator is Clinical Trials at Hoffmann-La Roche. The trial plans to enroll 800 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology