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Recruiting NCT07125235

NCT07125235 Reactive Driven Support for Treatment, Adherence, Resilience, and Thriving (reSTART) Clinical Trial

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Clinical Trial Summary
NCT ID NCT07125235
Status Recruiting
Phase
Sponsor University of California, San Francisco
Condition Behavioral Intervention
Study Type INTERVENTIONAL
Enrollment 270 participants
Start Date 2026-02-09
Primary Completion 2028-04-30

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
reSTART Objective Adherence Self-Monitoring and Postive Affect mHealth Interventionurine tenofovir point-of-care self-test

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 270 participants in total. It began in 2026-02-09 with a primary completion date of 2028-04-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Men who are living with HIV and use stimulants face many challenges and barriers that may interfere with remembering to take their HIV medication. Forgetting to take HIV medication puts men living with HIV at a greater risk of becoming virally unsuppressed. Researchers are doing this study to test if a remote intervention can help participants improve remembering to take their HIV medications and reduce the HIV viral load among men living with HIV who use stimulants.

Eligibility Criteria

Inclusion Criteria: * Prescribed antiretroviral therapy (ART) with a tenofovir-based regimen. * Documented virologic non-suppression, urine tenofovir testing without tenofovir detected, or self-reported adherence \<100%. * Reports stimulant use. * Has a mailing address within the U.S. * Currently has a smartphone with photo capabilities. Exclusion Criteria: * Have any health condition that may interfere with participation or the ability to provide informed consent, including any debilitating or life-threatening conditions. * Not prescribed ART. * Unwilling to perform urine self-testing or to attend a local Quest site for viral load monitoring. * Unable to provide a hair sample of \~50-100 strands of hair that are non-gray, not bleached, and at least 1cm in length

Contact & Investigator

Central Contact

Shivani Mahuvakar

✉ shivani.mahuvakar@ucsf.edu

📞 415-878-6384

Principal Investigator

Matthew Spinelli, MD, MAS

PRINCIPAL INVESTIGATOR

University of California, San Francisco

Frequently Asked Questions

Who can join the NCT07125235 clinical trial?

This trial is open to male participants only, aged 18 Years or older, up to 70 Years, studying Behavioral Intervention. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07125235 currently recruiting?

Yes, NCT07125235 is actively recruiting participants. Contact the research team at shivani.mahuvakar@ucsf.edu for enrollment information.

Where is the NCT07125235 trial being conducted?

This trial is being conducted at San Francisco, United States.

Who is sponsoring the NCT07125235 clinical trial?

NCT07125235 is sponsored by University of California, San Francisco. The principal investigator is Matthew Spinelli, MD, MAS at University of California, San Francisco. The trial plans to enroll 270 participants.

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