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Recruiting NCT05225792

NCT05225792 Rapid Rehabilitation to Treat Lower Extremity Trauma

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Clinical Trial Summary
NCT ID NCT05225792
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Lower Limb Trauma
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2024-01-08
Primary Completion 2027-04-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Promis Physical Function QuestionnaireL TestNarrowing Beam Walking Test

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2024-01-08 with a primary completion date of 2027-04-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to find out if an advance balance perturbation training program can enhance the rehabilitation process by increasing weight-bearing strategies on the prosthetic or injured limb, and, help reduce stumbles and falls.

Eligibility Criteria

Inclusion Criteria: * Research participants will be eligible active duty service members and retired veterans. * Having lower limb trauma (transtibial and transfemoral amputations, bilateral amputations, and limb salvage). * Are enrolled in conventional rehabilitation at the participating military treatment centers. * Subjects with dysvascular disease will be excluded because compromised lower limb somatosensation and circulation are independently linked with poor postural stability and a history of frequent falls. * For subjects with amputations, the individual must be a community ambulator (i.e., K-Level 3 or 4). * For subjects with limb salvage, they will need to have an IDEO and be entered into the Return-to-Run training program. Exclusion Criteria: \- Subjects must not have excessive pain or other neuromuscular problems that preclude them from performing the test protocol.

Contact & Investigator

Central Contact

Christine Huyber, CCRP

✉ Huyber.Christine@mayo.edu

📞 (507) 266-0984

Principal Investigator

Kenton Kaufman, PhD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT05225792 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Lower Limb Trauma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05225792 currently recruiting?

Yes, NCT05225792 is actively recruiting participants. Contact the research team at Huyber.Christine@mayo.edu for enrollment information.

Where is the NCT05225792 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT05225792 clinical trial?

NCT05225792 is sponsored by Mayo Clinic. The principal investigator is Kenton Kaufman, PhD at Mayo Clinic. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology