NCT07715591 Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery
| NCT ID | NCT07715591 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, Los Angeles |
| Condition | Cataract |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2026-06-10 |
| Primary Completion | 2026-09-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2026-06-10 with a primary completion date of 2026-09-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial evaluates whether a standardized perioperative neuroplastic intervention: the STEIN Protocol (Strategies and Techniques for Enhancing Integration and Neuroplasticity), consisting of pain neuroscience education, guided imagery, and paced breathing, reduces intraoperative analgesic and anxiolytic requirements. Secondary outcomes include patient-reported pain, anxiety, satisfaction, and postoperative recovery following cataract surgery. Reduced intraoperative sedative and analgesic requirements may reflect improved patient comfort and autonomic regulation while minimizing medication-related adverse effects.
Eligibility Criteria
Inclusion Criteria: Adults undergoing elective cataract surgery under topical anesthesia who are able to provide informed consent and complete study procedures. Exclusion Criteria: Inability to provide informed consent Inability to comply with study procedures Complex or combined cataract surgery General anesthesia Medical, neurologic, psychiatric, or respiratory conditions interfering with study participation Requirement for modified anesthetic protocols Inability to complete postoperative breathing exercises or follow-up assessments
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07715591 clinical trial?
This trial is open to participants of all sexes, studying Cataract. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07715591 currently recruiting?
Yes, NCT07715591 is actively recruiting participants. Contact the research team at slin@jsei.ucla.edu for enrollment information.
Where is the NCT07715591 trial being conducted?
This trial is being conducted at Los Angeles, United States.
Who is sponsoring the NCT07715591 clinical trial?
NCT07715591 is sponsored by University of California, Los Angeles. The trial plans to enroll 300 participants.