Radiomics for Preoperative Jaw Cyst Differentiation
Trial Parameters
Brief Summary
This study focuses on jawbone cystic lesions, including odontogenic tumors like ameloblastoma and various cysts. Treatment approaches differ; ameloblastomas often require surgical excision due to potential recurrence and metastasis, while cystic lesions may be treated with curettage and marsupialization. Accurate preoperative diagnosis is crucial for optimal treatment outcomes, as inappropriate choices can lead to delayed treatment or overtreatment, affecting patient quality of life. Currently, there is no standard protocol for differential diagnosis, highlighting the need for a predictive diagnostic model. The study will be a multicenter, prospective machine learning research involving 300 patients across 12 centers. It aims to enhance a previously developed predictive model that integrates machine learning with CT radiomics. Patients will be grouped based on imaging modalities, with data processed uniformly to improve diagnostic predictions. Inclusion criteria ensure comprehensive preoperative data, while exclusion criteria eliminate incomplete or previously treated cases. The study seeks to optimize the model's performance and provide valuable clinical insights.
Eligibility Criteria
Inclusion Criteria: * first-time visitors who have not received other treatment interventions; * participants with complete preoperative medical records, imaging examinations, and imaging data; * participants who have undergone maxillofacial CT examination preoperatively, with complete CT data, no artifact interference in the lesion area, and a lesion size with the longest diameter of at least 2 cm; * participants who can tolerate surgical treatment, with specimens sent for routine pathological examination after surgery. Exclusion Criteria: * incomplete medical records, such as missing specialized examination and treatment operation records; * patients who received therapeutic operations at other hospitals at first diagnosis, not fully cured or with recurrence; * patients who did not undergo CT examination preoperatively, with incomplete CT data, severe artifact interference in the lesion area, or lesion size not meeting requirements; * lesions not submitted as specimens for examinatio