NCT06819449 Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients
| NCT ID | NCT06819449 |
| Status | Recruiting |
| Phase | — |
| Sponsor | South Valley University |
| Condition | Leprosy |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-12-20 |
| Primary Completion | 2025-12-10 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.
Eligibility Criteria
Inclusion Criteria: * Patients of both sexes with positive slit skin smear for m.leprae . Exclusion Criteria: * Contraindications to Multi drug therapy : * Patients with hypersensitivity to sulfa . * Patients with hypersensitivity to clofazimine or rifampcin. * pregnant or lactating women.