NCT06659731 Quantitative Sensory Testing to Study Pain Perception in Autism
| NCT ID | NCT06659731 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Eugenio Medea |
| Condition | Autism Spectrum Disorder (ASD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-07-17 |
| Primary Completion | 2025-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2024-07-17 with a primary completion date of 2025-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum. To achieve this goal, the quantitive sensory testing (QST), a controlled and replicable protocol, will be used, to assess perception in different sensory modalities: heat sensations, mechanical detection threshold and pain threshold. As secondary aim, the cortical processing of thermal painful stimuli will be collected through electroencephalography (EEG) in order to investigate if there are differences in the cortical processing of painful stimuli between clinical sample and control sample, and if it could be associated with differences in the subjective experience between the two groups. Finally, it will be explored the association between such differences, and indexes of psychopathology and dispositional measures.
Eligibility Criteria
Inclusion Criteria for the clinical sample: * Children and adolescent * age between 5 and 17 years old * Autism diagnosis according to DSM-V criteria Inclusion Criteria for the control sample: * healthy children and adolescent (without neurological, and psychiatric, diagnoses) * age between 5 and 17 years old Exclusion Criteria: Comorbidities with (for the clinical sample) or diagnosis of (for the control sample): * peripheral neuropaties; * psychiatric diagnosis as psychosis, * Tourette Syndrome, * neurological diagnoses as epilepsy, * sensory deficit or loss; * genetic diseases
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06659731 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 17 Years, studying Autism Spectrum Disorder (ASD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06659731 currently recruiting?
Yes, NCT06659731 is actively recruiting participants. Contact the research team at valentina.nicolardi@lanostrafamiglia.it for enrollment information.
Where is the NCT06659731 trial being conducted?
This trial is being conducted at Brindisi, Italy.
Who is sponsoring the NCT06659731 clinical trial?
NCT06659731 is sponsored by IRCCS Eugenio Medea. The trial plans to enroll 50 participants.