NCT07325175 Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
| NCT ID | NCT07325175 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Children's Hospital Medical Center, Cincinnati |
| Condition | Dystonia |
| Study Type | INTERVENTIONAL |
| Enrollment | 75 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2029-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 75 participants in total. It began in 2024-01-01 with a primary completion date of 2029-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are: How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)? Participants will: * Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task. * Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.
Eligibility Criteria
Inclusion Criteria: * For dystonia subjects: * Dx of dystonia (with and without DBS) * willingness and ability to complete study protocols. * For Typically Developing Controls: * normal developmental milestones * absence of any neuropsychiatric disorder * no significant medical condition. Exclusion Criteria: * history of epilepsy * presence of implanted medical devices (except DBS in dystonia subjects) * lack of cognitive or physical ability to complete study protocol.
Frequently Asked Questions
Who can join the NCT07325175 clinical trial?
This trial is open to participants of all sexes, aged 6 Years or older, up to 21 Years, studying Dystonia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07325175 currently recruiting?
Yes, NCT07325175 is actively recruiting participants. Visit ClinicalTrials.gov or contact Children's Hospital Medical Center, Cincinnati to inquire about joining.
Where is the NCT07325175 trial being conducted?
This trial is being conducted at Cincinnati, United States.
Who is sponsoring the NCT07325175 clinical trial?
NCT07325175 is sponsored by Children's Hospital Medical Center, Cincinnati. The trial plans to enroll 75 participants.