NCT06885463 PRP & PDO Threads in Treatment of Stress Incontinence
| NCT ID | NCT06885463 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Al-Azhar University |
| Condition | Stress Incontinence, Female |
| Study Type | INTERVENTIONAL |
| Enrollment | 10 participants |
| Start Date | 2025-03-01 |
| Primary Completion | 2025-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 10 participants in total. It began in 2025-03-01 with a primary completion date of 2025-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study will include 10 women with pure or predominant SUI symptoms, with severe urodynamic stress incontinence on urodynamics defined as loss of urine with sudden increases in abdominal pressure: eg, coughing, sneezing, or laughing). This will be conducted at the Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University. The purpose of study is to evaluate the efficacy and safety of platelets rich plasma combined with PDO threads in the treatment of stress incontinence in Egyptian women.
Eligibility Criteria
Inclusion Criteria: * Nonpregnant Women with SUI * Age between 20 to 45 years * Patients had a history of failed conservative treatment * Patients were on the waiting list for surgical treatment of SUI Exclusion Criteria: * Under anti-platelet agent treatment * Under NSAIDs * Platelet dysfunction syndrome * Critical thrombocytopenia * Hypofibrionogenaemia * Sepsis * Acute and chronic infections * Chronic liver disease * Anti-coagulation therapy * History of malignancy * Pregnancy * history of active malignant pathology * mental disorders making them unable to give consent * genitourinary fistula * pelvic organs prolapse stage \>2 according to the Pelvic Organ Prolapse Quantification system, and detrusor overactivity on urodynamics.
Frequently Asked Questions
Who can join the NCT06885463 clinical trial?
This trial is open to female participants only, aged 20 Years or older, up to 45 Years, studying Stress Incontinence, Female. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06885463 currently recruiting?
Yes, NCT06885463 is actively recruiting participants. Visit ClinicalTrials.gov or contact Al-Azhar University to inquire about joining.
Where is the NCT06885463 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT06885463 clinical trial?
NCT06885463 is sponsored by Al-Azhar University. The trial plans to enroll 10 participants.