← Back to Clinical Trials
Recruiting NCT05641142

NCT05641142 Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic Telangiectasia

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05641142
Status Recruiting
Phase
Sponsor University Hospital, Clermont-Ferrand
Condition Hereditary Hemorrhagic Telangiectasia
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2023-04-07
Primary Completion 2029-04

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
monitoring the use of anticoagulant and/or antiplatelet therapy in patients with osler rendering disease

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2023-04-07 with a primary completion date of 2029-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to evaluate in real life, in patients with Hereditary Hemorrhagic Telangiectasia (HHT), the tolerance of the strategy of use of anticoagulant and/or antiplatelet, by comparing a new exposure period (first trimester of treatment) to a period of reference non-exposure (last trimester before start of treatment).

Eligibility Criteria

Inclusion Criteria: * Patient with Rendu-Osler disease with an indication of antiplatelet and/or anticoagulant introduced for less than 3 months (inclusion period within 3 months of exposure) * Age \> 18 years old * Patient able to understand and agree to participate in the study * Affiliation to a social security system Exclusion Criteria: * Patient with an indication of antiplatelet and/or anticoagulant but for whom treatment has not been introduced or introduced for more than 3 months * Refusal to participate * Pregnant woman or who are breast feeding * Patients under maintenance of justice, wardship or legal guardianship

Contact & Investigator

Central Contact

Lise Laclautre

✉ promo_interne_drci@chu-clermontferrand.fr

📞 334.73.754.963

Principal Investigator

Vincent GROBOST

PRINCIPAL INVESTIGATOR

University Hospital, Clermont-Ferrand

Frequently Asked Questions

Who can join the NCT05641142 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Hereditary Hemorrhagic Telangiectasia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05641142 currently recruiting?

Yes, NCT05641142 is actively recruiting participants. Contact the research team at promo_interne_drci@chu-clermontferrand.fr for enrollment information.

Where is the NCT05641142 trial being conducted?

This trial is being conducted at Angers, France, Bordeaux, France, Boulogne-Billancourt, France, Caen, France and 11 additional locations.

Who is sponsoring the NCT05641142 clinical trial?

NCT05641142 is sponsored by University Hospital, Clermont-Ferrand. The principal investigator is Vincent GROBOST at University Hospital, Clermont-Ferrand. The trial plans to enroll 100 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology