← Back to Clinical Trials
Recruiting NCT05221372

NCT05221372 ProSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors (START-TKI)

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05221372
Status Recruiting
Phase
Sponsor Erasmus Medical Center
Condition Non Small Cell Lung Cancer
Study Type OBSERVATIONAL
Enrollment 1,300 participants
Start Date 2017-02-02
Primary Completion 2031-01-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,300 participants in total. It began in 2017-02-02 with a primary completion date of 2031-01-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study is perfomed with adult patients with non-small cell lung cancer treated with tyrosine kinase inhibitor. The objective is to collect repeated samples of blood from patients (starting) on a tyrosine kinase inhibitor, for liquid mutation testing, and pharmacokinetic analysis.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years * Able to understand the written informed and able to give informed consent * Locally advanced or metastatic NSCLC with oncogenic driver mutation * Treatment with TKI according to standard of care Exclusion Criteria: * Unable to draw blood for study purposes

Contact & Investigator

Central Contact

Anne-Marie Dingemans, MD, PhD

✉ a.dingemans@erasmusmc.nl

📞 +31107040704

Principal Investigator

Anne-Marie Dingemans, MD, PhD

PRINCIPAL INVESTIGATOR

Erasmus Medical Center

Frequently Asked Questions

Who can join the NCT05221372 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Non Small Cell Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05221372 currently recruiting?

Yes, NCT05221372 is actively recruiting participants. Contact the research team at a.dingemans@erasmusmc.nl for enrollment information.

Where is the NCT05221372 trial being conducted?

This trial is being conducted at Rotterdam, Netherlands.

Who is sponsoring the NCT05221372 clinical trial?

NCT05221372 is sponsored by Erasmus Medical Center. The principal investigator is Anne-Marie Dingemans, MD, PhD at Erasmus Medical Center. The trial plans to enroll 1,300 participants.

Related Trials

Related Intelligence Guides

In-depth guides covering this condition's trials, eligibility, and what to expect.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology