NCT07062445 Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis
| NCT ID | NCT07062445 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hospital Israelita Albert Einstein |
| Condition | Meningitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 600 participants |
| Start Date | 2026-03-29 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 600 participants in total. It began in 2026-03-29 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Prospective, multicenter, observational clinical registry of pediatric patients with acute infectious meningitis across approximately 20 public and private hospitals in Brazil. The study will include children under 18 years of age with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.
Eligibility Criteria
Inclusion Criteria: * Fever (axillary temperature ≥37.8°C) followed by two or more of the following symptoms\*: severe headache, vomiting, altered consciousness (confusion, drowsiness, or irritability), photophobia (increased sensitivity to light), presence of seizures OR * Fever accompanied by at least one meningeal irritation sign, such as neck stiffness, Kernig's sign, or Brudzinski's sign OR * Sudden onset of fever and appearance of petechial skin rash or hemorrhagic suffusions * In children younger than two years, in addition to the presentations listed above, consider fever with any of the following: irritability, persistent crying, somnolence, or bulging fontanelle. Exclusion Criteria: * Refusal to provide consent for study participation
Contact & Investigator
Henrique A Fonseca
STUDY CHAIR
Hospital Israelita Albert Einstein
Frequently Asked Questions
Who can join the NCT07062445 clinical trial?
This trial is open to participants of all sexes, up to 17 Years, studying Meningitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07062445 currently recruiting?
Yes, NCT07062445 is actively recruiting participants. Contact the research team at anna.gomes@einstein.br for enrollment information.
Where is the NCT07062445 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT07062445 clinical trial?
NCT07062445 is sponsored by Hospital Israelita Albert Einstein. The principal investigator is Henrique A Fonseca at Hospital Israelita Albert Einstein. The trial plans to enroll 600 participants.