NCT05183971 Proprioceptive Deficits in Degenerative Cervical Myelopathy

Trial Parameters

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Brief Summary

Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control. DCM usually presents with body incoordination, hand clumsiness and gait disturbance associated with proprioceptive dysfunction that hinders the physical performance and functions. In this study, a non-invasive assessment protocol on proprioception will be developed for detecting subtle proprioceptive deficits at the early stage of disease through simple Physical Performance Tests for population older than 45. By adopting the physical performance tests as the diagnostic predictors of DCM, we aim to avoid the development of devastating consequences and disabilities.

Eligibility Criteria

Inclusion Criteria: * Chinese * Aged 50 or above * With radiological evidence of degenerative cervical myelopathy, both symptomatic and asymptomatic * Nurick grade less than 3 Exclusion Criteria: * Non-Chinese ethnicity * Aged under 50 * without any radiological proof of cervical myelopathy * Active problems of tuberculosis spine, lumbar spinal diseases, and other problems causing pain or deformities over the limbs that may affect their balance and movement * Presents with extra-pyramidal or other disorders involving the cerebellum or frontal lobe of the cerebrum leading to poor balance and gait disturbance * Previous spinal operation with residual disturbance in balance or gait * Non-communicable patients with insufficient cognitive ability to express their symptoms clearly * Non-walker * Blind or deaf

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