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Recruiting NCT06909240

Progressive Gait Training After First-time Deep Venous Thrombosis: Clinical Effectiveness and Involved Mecanisms (The DVT-Cph RCT)

◆ AI Clinical Summary

This study tests whether a personalized walking exercise program, combined with standard blood clot treatment, can improve quality of life for people who have had their first deep vein thrombosis (blood clot) in the leg. Researchers will compare this exercise program to standard care alone to see which approach helps patients feel better and function better in daily life.

Key Objective: The trial is testing whether progressive gait training combined with standard care can improve quality of life and reduce complications in patients recovering from their first leg blood clot.

Who to Consider: Patients who have recently been diagnosed with their first deep vein thrombosis in the lower leg and are interested in participating in a structured walking exercise program should consider enrolling.

Trial Parameters

Condition Deep Vein Thrombosis (DVT)
Sponsor Hvidovre University Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 152
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-11-15
Completion 2028-04-01
Interventions
Progressive gait trainingStandard Care (in control arm)

Brief Summary

The DVT-Cph RCT aims to investigate: 1. if progressive gait training in combination with standard care is superior to standard care on quality of life in patients with first time lower extremity deep venous thrombosis (clinical effectiveness part). 2. the association between progressive gait training and disease progression, late complications such as post throbotic syndrome, and severity of venous thromboembolism conditions in patients with first time lower extremity deep venous thrombosis (mechanistic part).

Eligibility Criteria

Inclusion Criteria: * 18 years or above * First time lower extremity DVT * Hospitalized at the Emergency Department * Can cooperate cognitively and physically (patient reported) Exclusion Criteria: * Patients without a Danish social security number * Terminal patients * Patients who do not understand or speak Danish

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